5 A patient comes into your doctors office (you specialize inimmunolo...

5. A patient comes into your doctorâ€™s office (you specialize in immunology and allergy) with a...

90.2K

Verified Solution

Question

Medical Sciences

5. A patient comes into your doctorâ€™s office (you specialize inimmunology and allergy) with a problem. Every time they get agastro-intestinal infection, they have a very severe inflamed gut.This doesnâ€™t happen when they get either respiratory or skininfections. When you biopsy the iliac and mesenteric lymph nodes,you donâ€™t find any B or T cells that are responsive to theinfection, which is a bit surprising. Based on the role of LN andGALT, explain why the above situation is unusual. Suggest anexplanation for what is occurring in this patient, and propose amethod for potentially helping them.

Answer & Explanation Solved by verified expert

3.9 Ratings (497 Votes)

ANS A patient comes into doctors office witha problem Every time they get a gastrointestinal infection theyhave a very severe inflamed gutbut this doesnt happen when they get either respiratory or skininfectionswhen biopsy the iliac and mesentric lymph nodes it didnt findany B or T cells that are responsive to the infection which is abit surprisingBased on the role of LN and GALT the above situation is unusualbecauseLN Lymph Node GALT Gutassociated lymphoid tissueBecause of the gut associated immune system does not allow theharmful intestinal antigens from the systemic circulation and thisgut associated immune system induces systemic tolerance againstluminal See Answer

Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:

Unlimited Question Access with detailed Answers
Zin AI - 3 Million Words
10 Dall-E 3 Images
20 Plot Generations
Conversation with Dialogue Memory
No Ads, Ever!
Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!

Become a Member