4. Imagine a gene promoter is located in “closed†chromatin –meaning the gene can’t be expressed – and you wish to turn on geneexpression. Describe 3 changes you can make to the DNA (or proteinsthat interact with DNA) to turn on gene expression. (There may bemore than 3 correct answers but you only need to give three.)
5. Imagine the opposite scenario to #4: a gene is currentlyactively expressed and you wish to turn OFF gene expression. Whatchanges can you make to turn off this gene?