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4. (10 pts) Hemoglobin S or sickle cell hemoglobin forms fibers in red blood cells because of...

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Biology

4. (10 pts) Hemoglobin S or sickle cell hemoglobin forms fibersin red blood cells because
of a Glu→Val mutation on the surface of the protein. The mutatedresidue interacts
with Leu and Phe residues located on the surface of a differentprotein molecule. This
interaction drives the formation of the fibers. Explain why higherconcentrations are needed to form fibers at lower temperatures.

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4.4 Ratings (1086 Votes)
Ans In sickle cell hemoglobin the changed or mutated amino acid is hydrophobic Valine amino acid in place of glutamic acide in normal hemoglobine Hydrophobic means fear of water    See Answer
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