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30 year Female with two year history of weight gain, hirsutism, easy bruising and oligomenorrhea. The...

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Medical Sciences

30 year Female with two year history of weight gain, hirsutism,easy bruising and oligomenorrhea. The doctor notes HT (BP 180/110)and muscle weakness. The laboratory data showed the followingresults: 9 am cortisol 600 nmol/L (200-700), Low dose dexamethasonesuppression test - Basal 630 nmol/L- 48h 470 nmol/L (normal <50nmol/L), Urine free cortisol: 1250 nmol/L (<250), Plasma ACTH:undetectable. What do you think the cause of her symptoms wouldbe?

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3.5 Ratings (488 Votes)
The cause of her symptoms might be hypersecretion of glucocorticoids resulting in a syndrome called cushings syndrome Hypersecretion of glucocorticoids may be due to tumor of adrenal cortex or may be also due to exogenously    See Answer
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