3. In mice, genes for albinism (a), chronic inflammation (i), and reduced sense of smell (r)...

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Biology

3. In mice, genes for albinism (a), chronic inflammation (i),and reduced sense of smell (r) are linked.  You initiallycrossed a mouse that is homozygous dominant for all three traitswith a mouse that is homozygous recessive for all threetraits.  You then crossed several of the resultingF1 offspring to mice that are homozygous recessive forall three traits.  You observe the following phenotypesin the offspring:

colored, healthy, normal smell sense

41

albino, chronically inflamed, reduced smell sense

45

colored, chronically inflamed, reduced smell sense

11

albino, healthy, normal smell sense

12

colored, healthy, reduced smell sense

2

albino, chronically inflamed, normal smell sense

3

colored, chronically inflamed, normal smell sense

14

albino, healthy, reduced smell sense

16

a. (3 points) Diagram a map between these three genes andcalculate the map distances between the genes.

b. (3 points) Calculate thecoefficient of coincidence and the interference values for doublecrossovers amongst these genes.

c. (2 points) Using the interferencevalue calculated in part (b), how many doublerecombinant F2 progeny will you observe if you continueto breed your F1 mice until you have 200 totaloffspring?

d. (2 points) If a fourth gene (z)exhibits 50% recombination with gene i, 36% recombination with genea and 50% recombination with gene r, is this gene on the samechromosome or a separate chromosome?  If gene z is on thesame chromosome as the other three genes, indicate its location bycopying and modifying your genetic map from part (a).

Please for part c and d explain itwith detail because i have more problem with part c and d , thankyou

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