22. You are studying a toxin that prevents RAS, a GTPase from hydrolyzing GTP. You find...

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Biology

22. You are studying a toxin that prevents RAS, a GTPase fromhydrolyzing GTP. You find that this toxin increase the amount ofcell growth. Please explain this finding.

23. You find that some cells have mutations that permanentlydeactivate Raf in this pathway. Please state whether you agree orthe Ras-affecting drug from the previous question will increase theamount of cell growth in the inactive Raf mutants.

Agree or Disagree?

Answer & Explanation Solved by verified expert
4.0 Ratings (627 Votes)
1Ras protein has a GTPase binding domain and when it is bound to GTP it is in active form Ras then binds to protein kinases activating them to phosphorylate downstream signalling    See Answer
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