2. Describe the mechanism of targeting of proteins to thesecretory pathway. Be sure to provide the step-by-step molecularmechanism of entry of proteins into the ER.
3. Outline an experimental progression involving site-directedmutagenesis to test the hypothesis that basic (positive) aminoacids are important for opening a voltage gated ion channel.
Part 2 1. Discuss the difference between a genomic and cDNAlibrary. Give details with respect to the preparationtechniques.
