2. Describe the mechanism of targeting of proteins to the secretory pathway. Be sure to provide...

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Medical Sciences

2. Describe the mechanism of targeting of proteins to thesecretory pathway. Be sure to provide the step-by-step molecularmechanism of entry of proteins into the ER.
3. Outline an experimental progression involving site-directedmutagenesis to test the hypothesis that basic (positive) aminoacids are important for opening a voltage gated ion channel.
Part 2 1. Discuss the difference between a genomic and cDNAlibrary. Give details with respect to the preparationtechniques.

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Ans 2 The secretory pathway refers to the EREndoplasmic reticulum Golgi Apparatus and the vesicles that travel in between them as well as the cell membrane Its named secretory for being the pathway by which the cell secretes proteins into the extracellular environment This pathway also processes proteins that will be membranebound whether in the cellular membrane or in the ER or Golgi membranes themselves as well as lysosomal enzymes and also any proteins that will live their lives in the secretory pathway itself It is responsible for the processing of proteins for export from the cell The synthesis of all See Answer

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