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1a. Many uridine molecules are inserted into some mitochondrial mRNAs in trypanosomes.  The uridine residues come from the...

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Biology

1a. Many uridine molecules are inserted into some mitochondrialmRNAs in trypanosomes.  The uridine residues come fromthe poly(U) tail of a donor strand!  Nucleosidetriphosphates do not participate in thisreaction.  Propose a reaction mechanism that accounts forthese findings.  (HINT:  relate this RNAediting to RNA splicing.)

b. Analysis of  p53 gene mutations in human tumorsshows that a large proportion of these mutations involve GC→ATtransitions originating at sites of DNAmethylation.  Propose a model to explain preferentialmutagenesis of this type at these sites.

Answer & Explanation Solved by verified expert
3.6 Ratings (621 Votes)
1aEditing in RNA transcript that encode proteins in the mitochondriaof trypanosomes In this case    See Answer
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