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  3. 1. the carboxylic acid group of an amino acid has

1. The carboxylic acid group of an amino acid has a pKa of approximately 2. However,...

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Chemistry

1. The carboxylic acid group of an amino acid has a pKa ofapproximately 2. However, carboxylic acids like benzoic acid andacetic acid have pKas in the range of 4-5 pKa units. Explain whythe carboxylic acid of an amino acid is more acidic.

2. Consider the amino acid arginine: a. At physiological pH (pH= 7.4), what is the predominant form in solution? b. What percentof the carboxylic acid group is ionized at this pH? c. What percentof the amino group is ionized at this pH?

Answer & Explanation Solved by verified expert
3.9 Ratings (549 Votes)
1Basically the acidicity of COOH group depends on how muchhydroxyl bond is polarized The more the common electron pair of OHis withdrawed towards oxygen the more    See Answer
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