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1.

Suppose a researcher is interested in carrying out a phase IIclinical trial in order to assess the effectiveness of fourdifferent doses of an investigational new drug. Assume thefollowing table represents the summary statistics revolving aroundthe number of adverse events in the four fasting glucoses among thegroups.

Fasting Glucose	Treatment Group
124	1
124	1
125	2
134	2
138	2
137	2
136	2
119	1
124	3
120	1
116	3
124	3
127	3
129	1

A) Calculate the MSW.

B) Calculate the MSB

a		A) MSW=154.741 B) MSB=31.226
b		A) MSW=186.198 B) MSB=29.714
c		A) MSW=194.689 B) MSB=21.777

2.

A researcher is interested in the effectiveness of a new asthmamedication at increasing the forced vital capacity (FVC) inchildren. The medicated spray to be used via inhaler has moved intophase II of clinical trials where five different treatment dosesare being tested against the control best standard of care. Supposethe following incomplete ANOVA table summarizes the preliminaryanalysis for the study.

	Sum of Squares	df	Mean Square
Between Groups	4032.2
Within Groups		439
Total	7492.7

A) Complete the ANOVA table

B) Calculate an F statistic and a pvalue.

a		A) SSW=3469.5, dfB=5, dfT=444,MSB=806.44, MSW=7.90 B) F=102.1, pvalue ~0
b		A) SSW=2561.2, dfB=10, dfT=125,MSB=502.14, MSW=11.2 B) F=123.8, pvalue ~1
c		A) SSW=1259.0, dfB=15, dfT=236,MSB=678.24, MSW=9.11 B) F=99.5, pvalue ~0