1) Selective IgA Deficiency is the most common type of immunodeficiency reported for Caucasian populations. It...

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Biology

1) Selective IgA Deficiency is the most common type ofimmunodeficiency reported for Caucasian populations. It is alsostrongly associated (by statistics, not because of co-location on achromosome) with multiple types of of autoimmune disorders,including Graves Disease, Systemic Lupus Erythematosus, and Type IDiabetes.
Given the concepts embedded in the Hygiene hypothesis and whatwe have managed to figure out about the role of IgA in humanimmunity, what does this observed association between IgAdeficiency and autoimmunity suggest to you about:
a) the role of IgA in educating or training our immuneresponses?

b) the development of autoimmunity without the presence of IgAat our mucosal barriers?

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Selective IgA deficiency is been found with frequency of 1 in 600 in Caucasian race In current definition if serum level of IgA falls below 007 glt with normal IgG and IgM levels in individuals above 4 age is considered as to have See Answer

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