1 Please explain why noncompetitive inhibition where it isobserved e...

1. Please explain why â€œnoncompetitive inhibitionâ€- where it is observed experimentally- is more likely to be...

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Chemistry

1. Please explain why â€œnoncompetitive inhibitionâ€- where it isobserved experimentally- is more likely to be a coincidence than areveal of something profound in the mechanism of an enzyme (incontrast to competitive and uncompetitive inhibition).

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4.4 Ratings (639 Votes)

Sol Noncompetitive inhibition lowers only Vmax and binds to a site other than catalytic allosteric site on the enzyme By doing so they change the structural configuration of the enzyme cleft probably by disrupting Hydrogen bonding or hydrophobic interactions This also makes enzymesubstrate binding See Answer

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1. Please explain why â€œnoncompetitive inhibitionâ€- where it is observed experimentally- is more likely to be...