1. Ms Duffy is 28 years old and wears spectacles. Over the last three years her...
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1. Ms Duffy is 28 years old and wears spectacles. Over the lastthree years her vision has been worsening even with spectacles. Shewas examined by an eye doctor and diagnosed to have thinner andsteeper than normal corneas with vision impairment in both eyes butmore in the left than right eye. Her corneal condition and visionwere expected to continue to worsen without intervention. Thus, theeye doctor performed a negligibly invasive treatment procedure onher eyes, first in the left eye and six months later in the righteye. The treatment improved her vision in both eyes. Answer thefollowing sub-questions separately.
1. Which corneal disease did Ms Duffy develop? (1 mark)
2. What could be the effect/s of this corneal disease on MsDuffy’s vision and why? (1 mark)
3. What are the two most common likely causes of this disease?(1 mark)
4. From your understanding of the structure of the cornea, stateprimarily which part/s of the cornea is/are compromised in thisdisease? (1 mark)
5. What are the main clinical and histopathological features ofthis disease?
6. Which pathophysiological mechanisms are activated in thisdisease? Explain three of the mechanisms.
7. Explain the basic principle underlying treatment of MsDuffy’s disease. (1 mark)
1. Ms Duffy is 28 years old and wears spectacles. Over the lastthree years her vision has been worsening even with spectacles. Shewas examined by an eye doctor and diagnosed to have thinner andsteeper than normal corneas with vision impairment in both eyes butmore in the left than right eye. Her corneal condition and visionwere expected to continue to worsen without intervention. Thus, theeye doctor performed a negligibly invasive treatment procedure onher eyes, first in the left eye and six months later in the righteye. The treatment improved her vision in both eyes. Answer thefollowing sub-questions separately.
1. Which corneal disease did Ms Duffy develop? (1 mark)
2. What could be the effect/s of this corneal disease on MsDuffy’s vision and why? (1 mark)
3. What are the two most common likely causes of this disease?(1 mark)
4. From your understanding of the structure of the cornea, stateprimarily which part/s of the cornea is/are compromised in thisdisease? (1 mark)
5. What are the main clinical and histopathological features ofthis disease?
6. Which pathophysiological mechanisms are activated in thisdisease? Explain three of the mechanisms.
7. Explain the basic principle underlying treatment of MsDuffy’s disease. (1 mark)
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