Logo
Home Study Material Contact Search
AI Chat FREE
  1. sciences
  2. biology
  3. 1. in what part of a hepatocyte would a drug inter

1. In what part of a hepatocyte would a drug interaction involving CYP enzymes most likely occur? A....

50.1K

Verified Solution

Question

Biology

1. In what part of ahepatocyte would a drug interaction involving CYP enzymes mostlikely occur?

A. Endoplasmic reticulum

B. Lysosomes

C. Golgi apparatus

D.Outer cell membrane

E. Nucleus membrane

2. Simvastatin is at higher risk of initiating rhabdomyolysiswhen co-administered with all except the following?

A. Anti-IL-6 therapy (tocilizumab)

B. Strong CYP3A4 inhibitors

C. Grapefruit juice

D. Mechanism-based CYP3A4 inhibitors

E. Hepatocyte OATP inhibitors

Answer & Explanation Solved by verified expert
4.4 Ratings (878 Votes)
Q1 Correct option A Endoplasmic Reticulum Reason Cytochrome p450 is found primarily in proteinprocessing organelles such as Endoplasmic Reticulum It is an enzyme with various isotypes with roles in oxidation reactions involving fat steroids and xenobiotic    See Answer
Get Answers to Unlimited Questions

Join us to gain access to millions of questions and expert answers. Enjoy exclusive benefits tailored just for you!

Membership Benefits:
  • Unlimited Question Access with detailed Answers
  • Zin AI - 3 Million Words
  • 10 Dall-E 3 Images
  • 20 Plot Generations
  • Conversation with Dialogue Memory
  • No Ads, Ever!
  • Access to Our Best AI Platform: Flex AI - Your personal assistant for all your inquiries!
Become a Member

Other questions asked by students

Calculus
1.2K views

The first four terms of a geometric sequence are given. Find a12.an = {3, -6,...

Statistics
1.2K views

X 64 2 62 5 and o 3 8 indicate on the curve where t...

Finance
1.2K views

Assume you have just been hired as a business manager of Pamela’s Pizza, a regional pizza...

Mechanical Engineering
1.2K views

Would you recommend the use of magnetic particle testing for the detection of surface cracks in...

Basic Math
1.2K views

The type of household for the U.S. population and for a random sample of 411 households...

Advance Math
1.2K views

Show that the connected sum of two compact surfaces is a compact surface.

Accounting
1.2K views

Fauna Inc has the following items at year-end: Cash in First Bank                                                                  $15,000 Postdated checks                                                                         $450 Bank overdraft in checking account at Second Bank               $400 Savings...

Biology
1.2K views

5 Which of the following plasma proteins fun in the transport of molecules across the...

Geometry
1.2K views

125 0 V X W In the diagram of circle C mZVWX is 43 What...

Accounting
1.2K views

QP Corporated sold 5,350 units of its product at $46,50 per unit during the year...

Accounting
1.2K views

On September 1, 2020, Zara Co. loaned $5,000 cash to Zum Inc. and received a...

Accounting
1.2K views

Vaughn City College sold season tickets for the 2018 football season for $252000. A total...