1. Gillespie syndrome (GS) is a rare genetic disorder. The disorder is characterized by having part...
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1. Gillespie syndrome (GS) is a rare genetic disorder. Thedisorder is characterized by having part of the iris missing,ataxia, and, in most cases, intellectual disability. It is termedas a heterogenous disorder because it can be inherited eitherthrough an autosomal dominant pattern or through an autosomalrecessive pattern. Two parents are heterozygous for GS.
A. Assuming that the condition is following an autosomaldominant pattern, what are the ratios or percentages of thegenotypes AND phenotypes for the possible offspring?
B. Assuming that the condition is following an autosomalrecessive pattern, what are the ratios or percentages of thegenotypes AND phenotypes for the possible offspring?
C. List three examples EACH for autosomal recessive, autosomaldominant and X-linked inheritance patterns.
1. Gillespie syndrome (GS) is a rare genetic disorder. Thedisorder is characterized by having part of the iris missing,ataxia, and, in most cases, intellectual disability. It is termedas a heterogenous disorder because it can be inherited eitherthrough an autosomal dominant pattern or through an autosomalrecessive pattern. Two parents are heterozygous for GS.
A. Assuming that the condition is following an autosomaldominant pattern, what are the ratios or percentages of thegenotypes AND phenotypes for the possible offspring?
B. Assuming that the condition is following an autosomalrecessive pattern, what are the ratios or percentages of thegenotypes AND phenotypes for the possible offspring?
C. List three examples EACH for autosomal recessive, autosomaldominant and X-linked inheritance patterns.
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