1 For the past two decades genetic mapping has usually involved genetic markers with molecular...

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1 For the past two decades genetic mapping has usually involved genetic markers with molecular phenotypes than genes with more traditional phenotypes Discuss some of the advantages of using molecular markers for mapping that have made them the predominant ones used for mapping Besides the assay used to determine the phenotype what other part of the standard mapping procedure might be different when molecular markers are used 2 Consider three genes in Saccharomyces cerevisiae the mutant alleles are a b and c while the wild type alleles are a b and c a and b are on different chromosomes while a and c are linked Draw the tetrads that arise under the following situations a Strains that are mutant for a but wild type for b are crossed to ones that are wild type for a but mutant for b The F1 is allowed to sporulate and the tetrads are isolated and analyzed Diagram the expected result b Strains that are mutant for a but wild type for care crossed to ones that are wild type for a but mutant for c The F is allowed to sporulate and the tetrads are isolated and analyzed Diagram the expected result if the crossover does not occur between the a and c genes

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