1. An occurrence of a gene made larger by trinucleotiderepeats is:
Allelic expansion
Nucleotide expansion
Translocation mutation
Transformation
2. a chemical that can damage and/or change DNA iscalled a/an:
Allele
Endonuclease
Vector
Mutagen
3. An occurrence when a section of a chromosomerelocates itself to an entirely different (non-homologous)chromosome is called a/an:
Inversion mutation
Translocation mutation
Transformation mutation
Duplication mutation
4. The tandem repeat in the sequenceGGGAAGGGAAGGGAAGGGAAGGGAAG is:
GGA
GGGAA
GGAAG
GGAAGGG
A disease characterized by abnormally shaped hemoglobinis called:
Cystic Fibrosis
Sickle Cell Anemia
Marfan Syndrome
Leukemia
5. A point mutation that causes a substitution of a stopcodon with an amino acid and leads to the formation of a longerprotein is a:
Nonsense mutation
Missense mutation
Sense mutation
Frameshift mutation
6. Addition or deletion of nucleotides in a DNA sequenceis known as a:
Nonsense mutation
Missense mutation
Sense mutation
Frameshift mutation
7. The least severe type of chromosomal mutationis:
Point
Frameshift
Inversion
Translocation
8. Chemicals inserting themselves into DNA can causea:
Missense mutation
Nonsense mutation
Sense mutation
Frameshift mutation
9. A genetic condition caused by allelic expansionis:
Familial hypercholesterolemia
Fragile X syndrome
Alkaptonuria
Galactosemia
10. Which of the following is most likely the originalDNA strand if the mutated DNA strand is ATAGUUGATGUA ?
ATAGAAGATGAA
ATAGCCGATGCA
ATAGGGGATGGA
ATAGTTGATGTA
11. An unbalanced chromosomal mutation would includea/an:
duplication (insertion)
inversion
translocation
denaturation
12. Many translocation mutations are found to beinvolved with:
cancers
sickle cell anemia
Huntington disease
cystic fibrosis
13. A common repeat throughout the human genome that isapproximately 300 bases in length is called a/an:
EcoRI repeat
Hind repeat
Exo repeat
Alu repeat
14. A balanced chromosomal mutationincludes:
imprintation
denaturation
inversion
deletion
