1. An isolated population of chimpanzees was discovered on an island. Biochemical studies show that 1...

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Biology

1. An isolated population of chimpanzees was discovered on anisland. Biochemical studies show that 1 out of 9 chimpanzees inthis population are homozygous for a mutation in the gene encodingthe enzyme, hexokinase. This mutation completely inactivates theenzyme so that no activity is detected in the blood. A female whoexhibits hexokinase activity mates with a male who is a carrier ofthe hexokinase mutation. What is the probability that their firstbaby chimpanzee will be homozygous for the hexokinase mutation?Assume that the population is in Hardy-Weinberg equilibrium.
2. Cystic fibrosis is an autosomal recessive, fully penetranttrait in humans.Â Â Â Â A man who is unaffected bycystic fibrosis has two unaffected parents and a sister with cysticfibrosis.Â Â The man plans to marry a healthy woman, whowas adopted and has no knowledge about her biological parentsexcept that they are both Caucasian. The frequency of cysticfibrosis in the Caucasian population is 1/2500. Assuming that thispopulation is in Hardy-Weinberg equilibrium for the CFgene, what is the probability that this couple's first child willhave cystic fibrosis?

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4.0 Ratings (645 Votes)

1 It has been mentioned the male is a carrier of the hexokinase mutation the female exhibits hexokinase activity This means that male also has hexokinase activity and only one of the alleles coding for the enzyme is active and the other is not This means we should consider the female has hexokinase activity on both the alleles If we consider H as normal See Answer

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